The Van Horn Chamber of Commerce is a membership, volunteer-led organization. Its mission is to advance the Town of Van Horn by promoting the community, representing the unified voice of the community, and striving to ensure future prosperity. The principle office of the Chamber is at the Van Horn Convention Center and Visitors Bureau, Van Horn, Culberson County, Texas.

The Van Horn Chamber offers the opportunity for members to connect and network with other businesses on issues and activities pertaining to growth and success. The Chamber enables its members to stand out as business leaders in the community and influence development in the community.